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Research Sheds Light on Gluten Issues

January 25, 2012

We were intrigued in mid-2009 when research documented that celiac disease, an immune system reaction to gluten, has increased four-fold in the past half-century. We covered the research in an earlier blog, but the question still left on the table was, “Why has celiac disease increased so hugely?”

We set out to find the answers, by combing through scientific research, and came across some interesting information that may fill in the holes – and may give hope to the estimated 1-3% of people who cannot digest gluten properly.

A little background first, before we share our research trove with you. Research shows that celiac disease and gluten sensitivity are distinct problems, and in fact there may be two main types of Celiac Disease. Gluten is a protein that’s found in wheat, barley, rye and triticale (a wheat / rye hybrid). It’s only found in these four grains – so people who have celiac disease or are otherwise gluten-intolerant still have plenty of great choices of whole grains to enjoy. Gluten-free does not mean whole grain-free!

Our romp through the research turned up evidence that today’s wheat foods are, most likely, higher in gluten, which may account for the increased problems experienced by a small fraction of the population. The good news, though, is that we also found research that suggests ways to lower the gluten levels in wheat-based foods. We’ll organize this blog according to our good news findings. (Note: some of these ideas may also apply to barley and rye, but the research we found centers on wheat.)

Consider Ancient Grains

Different types of wheat have different numbers of chromosomes, and some studies show that the older wheats, with fewer chromosomes, tend to have lower levels of gliadins, the type of gluten proteins that seem to cause most sensitivities.

Einkorn, the oldest known type of wheat in our current food supply, has just 14 chromosomes, and is called a diploid wheat. Durum wheat (the kind most often used for pasta) and emmer are tetraploid wheats, with 28 chromosomes. Common wheat (used for most everything) and spelt have 42 chromosomes and are known as hexaploid wheats. Research shows that different tetraploid and hexaploid wheat varieties differ widely in gliadin levels, and it’s possible to select “individual genotypes with less Celiac Disease-immunogenic potential.”

Even if you’re not gluten-sensitive, you may want to consider some of the ancient grains. Research shows that Kamut has higher levels of antioxidants than some modern wheats, and that healthy plant sterols are higher in tetraploid wheats than in hexaploid wheats.

Organic May Trump Conventional Growing

We all understand that the foods we eat can make a big difference in the composition and health of our bodies. The old saying “You are what you eat” applies to plants, too.

We uncovered one intriguing study that found that varying levels of sulfur and nitrogen fertilizer can change the proteins in wheat. Different proteins, different sensitivities. Is there, perhaps, a connection between the widespread introduction of chemical fertilizers after World War II, and the four-fold increase in Celiac Disease during the same period?

The jury is still out. We’d like to see research that takes the next step, and compares the proteins in conventionally-farmed grains with organic grains.

Try the Old Ways of Making Bread

Once you’ve grown and harvested the wheat, how you make your bread may affect its gluten levels, too. Throughout most of mankind’s history, bread was made using a sourdough process based on lacto-fermentation. The process was slow, and results were uneven, so when modern yeast became available, sourdough breads became less common.

Now research shows us that lacto-fermentation of wheat has the potential to drastically reduce gluten levels. We found three studies along these lines. Our favorite study showed that sourdough bread produced with a particular strain of lacto-bacilli had gluten levels of 12 parts per million – where anything under 20 ppm is considered gluten-free. Bread made with the same wheat but without lacto-fermentation had gluten levels of 75,000 ppm.

Another cool thing about this study was that the Italian researchers lacto-fermented the flour, then dried it and used it in a conventional quick-baking process, one that could be compatible with modern bakeries. We love it when someone discovers ways to incorporate the best of the old ways into today’s realities – that’s what health through heritage is all about!

Share Your Thoughts and Your Research

I’m not a researcher – just a fascinated auto-didact – so some details of the studies cited here may have escaped me. I present the information above as speculation, and invite those doing actual research in this area to contact us with their latest findings. We’re excited by the range of research being conducted, and its potential for removing any barriers that stand in the way of all people being able to enjoy all whole grains! (Cynthia)

Comments

oats

My intolerance started with milk, then it was to "gluten." Though I do not have celiac disease started with oats. They were organic oats. Well, I thought steel-cut oat would be better. NO! They were worse. Then it was apples-fructose intolerance. (These were my own apples from my apple tree!).

Oats- Fructose Malabsorption

I had a blood test (Spectrall Cell; amino acids) done and came up with Fructose Deficiency which is here in the States, FM and perhaps Sorbitol foods. Wow...all my "healthy food buying" is gone now. Fructose in most all fruits, brown rice, and some veggies. Only white sugar can be used. Yep. So, also needing to not use yeast in breads. So, interested in Ancient Grains. Only one's own research helps FM (FODMAPS) persons cause here in the States it is little known..Australia has the best info and the blogs from people who know what to do....I can not eat oats; I react with fatigue right away.

Breads

You might look at Ezekiel bread. It's supposed to be made the way they did in ancient times. I have no idea how true this is, or if this would help. But, I wanted to pass the information on. It's available in most Kroger, HEB and I think WalMart stores. L.

RE: Fructose Malabsorption

Digestive problems like yours can indeed be challenging. Dietary approaches to fructose malabsorption can vary, so we can't begin to offer specific dietary advice to you. However, we do know that the ratio of fructose to glucose matters for some people, and the total fructose load may also matter. 

With that in mind, we can suggest that you turn to the USDA National Nutrient Database if you'd like to check the total fructose or the fructose: glucose ratio of any food. Go to http://ndb.nal.usda.gov/ and click on Start Your Search Here. Put in the name of a food, then find it in the search results list. You'll get a Basic Report on that food. Now here's the secret: Just under the name of the food on the report are the words "Full Report (All Nutrients)". If you click on that, most foods will include the breakdown of the sugars in a way that could be helpful to you in exploring what foods will meet your dietary requirements. Hope this helps. (Cynthia)

gluten

There is no mention of oat in your study.

whole grain wheat and gluten intolerance

Can substituting processed grains (including wheat, rye, and barley) with whole grain versions alleviate symptoms of gluten intolerance and even celiac disease?

substituting

Dear Chris,
No, whole grain wheat, rye and barley and foods made with them are also off-limits to people with gluten intolerance and celiac disease. But there are so many other grains you can enjoy!

Cynthia

thanks!

I love this entry. There is so much great information. You rock!

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