SEARCH HEALTH STUDIES

Whole Grains Linked with Good Metabolic Health, Especially for Heart Disease and Diabetes

Whole grains are an important part of a healthy diet, and researchers wanted to take a closer look at the relationship between eating whole grains and cardiometabolic health. In this study, researchers reviewed a collection of 25 systematic reviews and meta-analyses of randomized controlled trials (the “gold standard” in nutrition research) that addressed the relationship between whole grain consumption and metabolic health. Across the dataset, it was clear that “[whole grain] consumption plays a crucial role in improving key aspects of metabolic health,” especially in diabetes management, cholesterol management, blood pressure management, obesity and inflammation.
Food Funct. 2025 Oct 29. doi: 10.1039/d5fo03240g. Online ahead of print. (Huang H et al.)

Whole Grains Linked with Better Cognitive Function

If you want to keep your brain sharp, make sure you’ve got whole grains on your plate. In a study of 5,020 middle-aged and older adults in China, those eating the most whole grains had significantly higher scores of cognitive function, including better auditory verbal learning, better verbal fluency and more, as well as a lower risk of mild cognitive impairment.
Food Funct. 2025 Oct 27;16(21):8530-8537. doi: 10.1039/d5fo01862e. (Li Y et al.)

Whole Grain Labels Help Consumers Identify and Purchase Whole Grain Products

The best whole grain guidance is meaningless if consumers can’t find these products at the store. In this online experiment of 2,013 Australian adults, those seeing products with color-coded whole grain labeling were significantly more likely to identify the products highest in whole grains and express interest in purchasing them, compared with adults who were shown images of whole grain products that contained no special whole grain labeling. This research adds to the existing body of evidence that whole grain labels can be an effective public health tool.
Nutr Metab Cardiovasc Dis. 2025 Oct 9:104406. doi: 10.1016/j.numecd.2025.104406. Online ahead of print. (Sengupta A et al.)

Whole Grains Linked with Healthier Aging

Fad diets that replace high-quality carbohydrates like whole grains with meat pose a risk for aging down the road. In a study of 47,513 women, those eating the most high-quality carbohydrates (such as whole grains) at midlife were 31 percent more likely to age healthfully (free of chronic disease, cognitive impairments or poor mental health) 30 years later than those eating the fewest high-quality carbohydrates. Replacing just 5 percent of calories from refined carbohydrates, animal protein or total fat with high quality carbohydrates like whole grains was linked with an 8-16 percent higher likelihood of healthful aging. The study also found benefits related to higher-carbohydrate diets and higher fiber intake, as well as increased risks with refined carbohydrate intake.
JAMA Netw Open. 2025 May 1;8(5):e2511056. doi: 10.1001/jamanetworkopen.2025.11056. (Korat AVA et al.)

High-Quality Carbohydrates Like Whole Grains Linked with Healthier Aging

People who avoid carbohydrates may be doing their health a disservice, especially as they age. In a study of 47,513 women, eating more carbohydrates from high-quality sources (whole grains, fruits, vegetables and beans) was linked with significantly healthier aging over the thirty-year study period. Healthy aging was defined as not having major chronic diseases, not having cognitive and physical function problems, and having good mental health. Eating more total carbohydrates (from all sources) and eating more fiber were also significantly linked to healthier aging.
JAMA Netw Open. 2025 May 1;8(5):e2511056. doi: 10.1001/jamanetworkopen.2025.11056. (Korat AVA et al.)

Whole Grains Linked with Lower Risk of Type 2 Diabetes

When it comes to reducing your risk of type 2 diabetes, a diet with healthy carbohydrates should be a key part of your nutrition playbook. In this review, researchers analyzed 67 studies related to food groups and risk of type 2 diabetes, metabolic syndrome, and diabetes mortality. A high intake of whole grains was linked with a significantly lower risk of type 2 diabetes, with similar (though no quite as strong) tendencies for fruit and vegetable intake. A high intake of red meat, processed meat, and/or sugar sweetened beverages were all linked with a higher risk of type 2 diabetes. For other food groups, the risk of type 2 diabetes wasn’t statistically significant in either direction.
J Nutr. 2025 Mar 21:S0022-3166(25)00173-7. doi: 10.1016/j.tjnut.2025.03.021. (Banjarnahor RL et al.)

Whole Grains Linked with Lower Risk of Gum Disease

Periodontitis, or gum disease, can put people at risk for heart and lung diseases down the road. Researchers analyzed the whole grain and refined grain intake of 7,753 adults in the US and measured which of those adults had gum disease. Those eating the most whole grains and those who had the greatest ratio of whole grains to refined grains had a lower risk of gum disease. Specifically, every one-ounce serving of whole grains was linked with an 11 percent lower risk of gum disease.
Int J Food Sci Nutr. 2024 Nov 4:1-11. doi: 10.1080/09637486.2024.2420265. Online ahead of print. (Guo S et al.)

Exposing People to Whole Grains Improves Acceptability of Whole Grains

Just because someone says they don’t like whole grains, doesn’t mean we should write off their interest immediately. In fact, changing the food environment by simply exposing these people to whole grains is enough to change their attitudes, a new study shows. In this study, researchers provided 45 healthy adults with either refined grain or whole grain products to take home for six weeks. Researchers measured how much of the provided grain foods were eaten, and they measured if people associated different types of grains with either an unpleasant or pleasant taste before and after the study using an implicit association computer test with measured response times. The whole grain group consumed just as much of their provided grains as the refined grains group, and individuals who considered whole grains as unpleasant tasting before the study were significantly more likely to change their tune and consider whole grains to be pleasant tasting after being provided with the whole grain foods.
Front Nutr. 2024 Sep 30:11:1408256. doi: 10.3389/fnut.2024.1408256. eCollection 2024. (De Leon A et al.)

Eating Whole Grains Linked with Lower Risk of Liver Disease

Poor diet can be a risk factor for certain types of liver diseases, so researchers conducted a meta-analysis of studies to see how whole grain intake might relate to liver disease risk. Those eating the most whole grains had a 10% lower risk of developing any chronic liver disease than those eating the least. The results were especially pronounced for a certain subgroup of serious liver diseases. Eating whole grains was linked with a 35% lower risk of developing cirrhosis (a potentially fatal form of liver damage) and a 63% lower risk of chronic liver disease mortality.
Food Funct. 2024 Sep 30;15(19):9707-9717. doi: 10.1039/d4fo03077j. (Zhang Y et al.)

Eating 1 More Ounce of Whole Grains Daily Could Save Billions in Healthcare Costs and Reduce Carbon Emissions

China is the second most populous country in the world, meaning that dietary shifts at a national level could have drastic health, climate, and even financial impacts. In this modeling study, researchers estimated that if all adults in China were to eat about 1 more ounce of whole grains per day, the total indirect and direct healthcare savings related to type 2 diabetes, heart disease, and colorectal cancer alone would be an estimated $56.37 billion annually. Further, because whole wheat flour and brown rice tend to have lower carbon footprints than their refined counterparts, eating 1 more ounce of whole grains per day is projected to reduce carbon emissions by up to 5.72 million tons.
Journal of Integrative Agriculture. 2024 Aug. 23(8):2842-2852. doi: 10.1016/j.jia.2023.12.006. (Zhang X et al.)

Low Whole Grain Intake Linked with Early Onset Colorectal Cancer

Early-onset (diagnosed before age 50) colorectal cancer risk is thought to be influenced by diet and lifestyle factors, so researchers wanted to find out which foods might be involved with colorectal cancer risk. Using data from the Global Burden of Disease Study 2019, scientists found that a diet low in whole grains is one of the leading dietary risk factors for early onset colorectal cancer, ahead of diets high in red and processed meat and even diets low in fiber. 
Frontiers in Nutrition. 2024 May 31:11:1384352. doi: 10.3389/fnut.2024.1384352. eCollection 2024. (Su J et al.)

Whole Grains Linked with Improvements in Diabetes

Healthy carbohydrates like whole grains are part of the solution, not the problem, when it comes to diabetes. In this study, researchers analyzed 29 randomized controlled trials (the gold standard of nutrition research) to see how whole grains and ancient grains might impact health outcomes in people with diabetes. They found that brown rice significantly improved HbA1c (a measure of blood sugar control over time) and BMI (a measure of weight based on height), that oats significantly improved cholesterol, and that millet significantly improved body weight. However, given the different grains and research methods used, it was difficult for the researchers to draw broad conclusions across the whole group of grains, indicating that more research is needed to understand these effects. 
Nutr Metab Cardiovasc Dis. 2024 May;34(5):1110-1128. doi: 10.1016/j.numecd.2024.03.005. Epub 2024 Mar 7. (Magi CE et al.)

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