Whole grains

Researchers at Imperial College London conducted a meta-analysis of 25 studies involving almost two million people (and 14,500 cases of colorectal cancer) to assess the links between colorectal cancer and both whole grains and total dietary fiber. They concluded that there is a credible “dose-response” relationship between whole grain consumption and reduced cancer risk; they estimate that eating three or more servings of whole grains per day lowers colorectal cancer risk nearly 20%. Dietary fiber also reduces this risk, but cereal/grain fiber shows stronger benefits than other types of fiber.
British Medical Journal, 10 November 2011; 343:d6617 (Aune et al.)

To assess the benefits of whole grains for adolescents U.S. researchers reviewed dietary data from 4,928 adolescents aged 12-19, about evenly divided between boys and girls. They compared this data to several health measures, and found that, in both genders, those with the highest whole grain consumption had lower fasting insulin levels, and higher folate levels. Girls who ate the most whole grains also had lower C-peptide concentrations (a marker for good insulin function), while boys has lower homocysteine concentrations (a marker for reduced cardiovascular risk).
Journal of the American Dietetic Association, 3 Nov 2011 [Epub ahead of print] (Hur et al.)

Researchers from the University of Minnesota (including WGC Scientific Advisor Len Marquart) observed students at 10 schools in Minnesota and 7 schools in Texas, to see whether whole grain pancakes and tortillas can readily be substituted for similar refined products. For the study, foods with varying percentages of whole grain content were used. Using both aggregate plate waste measurements and student taste ratings, the scientists noted no difference in whole grain vs. refined grain pancake consumption at both elementary and middle / high schools, while consumption of whole grain tortillas was lower than refined tortillas. In general, elementary students were pickier than middle and high school students, and the use of whole white wheat boosted acceptance over whole red wheat. The researchers concluded that products such as those in the study would increase consumption of whole grains among children and youth.
Journal of the American Dietetic Association. September 2011; 111(9):1380-4

Recent research has shown that children’s acceptance of whole grains varies widely from food to food. Kids will happily consume some foods that are 100% whole grain, while turning down others in which only 10-15% of the grain is whole grain. Using this knowledge, it’s possible to design a roadmap for increasing kids’ consumption of whole grains, without risking “pushback” – an important consideration, since the only healthy nutrients are those that are actually consumed. In this study, Len Marquart, Elizabeth Arndt, and colleagues modeled the change in whole grain consumption that could be achieved by switching 15% to 50% of the refined grain to whole grain in breads, pizza crusts, pasta, breakfast cereals, muffins, waffles and other foods kids eat daily. They found that, without changing documented eating patterns in the children, they could raise consumption of whole grains from 6% of total grains to 28% of whole grains with this approach, while also reducing demographic disparities.
Journal of the American Dietetic Association. September 2011; 111(9):1322-8

Scientists in Boston analyzed data from 13,368 male doctors in the Physicians’ Health Study I to see how consumption of breakfast cereals might be associated with hypertension. After adjusting for smoking, BMI, alcohol consumption, produce consumption, activity, and diabetes history, they found that the risk of hypertension was lowest among those who ate the most breakfast cereal. The association was strongest for whole grain cereals.
Clinical Nutrition. August 23, 2011  [Epub ahead of print]

A group of 90 healthy college students were enrolled in an introductory course in nutrition at a university in the Midwestern United States. The class, which met three times a week, emphasized the role of a healthful lifestyle as a mechanism related to disease prevention. Traditional lectures were combined with “hands on” activities that incorporated concepts from Social Cognitive Theory. Four hours of total lecture and activity time were devoted to whole grains. By the end of the semester investigators found a significant increase in the consumption of whole grains in the group that completed the study. 
Journal of Nutrition Education and Behavior. 2011; 43 (4): 263-267 (Ha et al.)

The American Society for Nutrition brought together researchers to review the evidence regarding the health benefits associated with whole grains. Current scientific evidence indicates that whole grains play an important role in lowering the risk of chronic diseases, such as coronary heart disease, diabetes, and cancer, and also contribute to body weight management and gastrointestinal health.
Journal of Nutrition, May 2011;141(5):1011S-22S. Epub March 30, 2011

In a cross-over study conducted at the UK’s University of Surrey, researchers asked 14 healthy normal-weight adults to consume either two whole grain rolls (totaling 48g of whole wheat) or two control rolls with their normal diets. While researchers did not find the decrease in appetite they had been seeking, they were surprised to find a significant decrease in the subjects’ systolic blood pressure during the three weeks they ate the whole wheat rolls, and an increase in systolic pressure during the white-bread phase of the trial.
British Journal of Nutrition, April 18, 2011: 1-4 [Epub ahead of print]

Researchers at Tufts University, including Nicola McKeown, analyzed data from 2834 Framingham Heart Study participants aged 32-83 years old, to assess the relationship between whole grain consumption and body fat distribution. They found that people with the highest whole grain intake had less subcutaneous abdominal fat (fat under their skin) and less visceral abdominal fat (fat around their organs), while those with the highest refined grain intake had more of both types of abdominal fat, especially visceral fat. Visceral fat has been linked to higher risk for diabetes and heart disease.
American Journal of Clinical Nutrition. November 2010; 92(5):1165-71.

In a randomized control trial of 233 healthy, middle-aged volunteers, subjects spent 4 weeks consuming a run-in diet of refined grains, and then were randomly allocated to the control diet (refined), a whole wheat diet, or a whole wheat and whole oats diet for 12 weeks. Each group consumed 3 daily portions of the specific grains. Systolic blood pressure and pulse pressure were significantly reduced by 6 and 3 mm HG, respectively, in the whole grains groups compared to the control refined group. Researchers at the University of Aberdeen concluded that this blood pressure decrease would decrease the incidence of coronary artery disease and stroke by 15-25% respectively.
American Journal of Clinical Nutrition, October 2010; 92(4):733-40. Epub August 4, 2010