Whole grains

After following 21,376 male physicians for almost 20 years, Luc Djoussé and J. Michael Gaziano at Harvard found that those eating two to six servings of whole grain cereal a week reduced their risk of heart failure 22%, while those eating whole grains daily reduced risk by 28%. For this study, cereals with at least 25% whole grain or bran by weight were classified as whole grain.
Archives of Internal Medicine, October 2007; 167: 2080-2085

At the Harvard School of Public Health, researchers led by JS de Munter pooled data from six cohort studies including 286,125 participants, and found that a two-servings a day increment in whole grain consumption was associated with a 21% decrease in risk of type 2 diabetes.
PLoS Medicine, August 2007; 28;4(8):e261

Researchers at Harvard studied nearly 30,000 enrolled in the Women’s Health Study. Lu Wang’s team found that, over ten years, those who ate the most whole grains had an 11% lower chance of developing high blood pressure.
American Journal of Clinical Nutrition, August 2007; vol 86(2):472-9

That habitual whole grain consumption reduces the risk of both cardiovascular disease and diabetes has been well documented. Now, a recent study by the University of Minnesota’s David Jacobs shows that eating whole grains confers an even greater risk-reduction in mortality from inflammatory diseases. Jacobs and his colleagues followed more than 27,000 post-menopausal women for 17 years and concluded that “oxidative stress reduction by constituents of whole grain is a likely mechanism for the protective effect.”
American Journal of Clinical Nutrition, June 2007; vol 85(6):1606-1614

A study by Philip Mellen at Wake Forest University and colleagues measured atherosclerosis of the common carotid artery, and its progression over five years. Mellen’s team found that, among the 1178 men and women in the study, those who ate more whole grains had less unhealthy artherosclerotic thickening of the common carotid artery.
American Journal of Clinical Nutrition, June 2007; vol 85(6):1495-1502

A team of researchers led by Arthur Schatzkin studied data for almost half a million middle-aged men and women enrolled in the NIH-AARP Diet and Healthy Study, to learn whether fiber intake and/or whole grains might reduce the risk of colorectal cancer. In this analysis, total dietary fiber intake was not associated with a reduced risk of colorectal cancer, but both grain fiber and whole grains were shown likely to reduce the risk of colorectal cancer.
American Journal of Clinical Nutrition, May 2007; vol 85(5):1353-1360

A study of 150 college students found that higher whole grain intake was associated with lower BMI (Body Mass Index). Overall, students averaged only 0.7 servings per day of whole grain, and authors, led by Nick Rose, noted that low availability of whole grains on and around campus could be responsible for low intake.
Journal of Nutrition and Education Behavior, March 2007; vol 39 (2); 90-94

A team from the Dutch National Institute of Public Health and the Environment found that children who ate whole grains were 54% less likely to develop asthma and 45% less likely to develop wheezing than children who did not eat whole grains.
Thorax, December 2006; 61(12):1048-53

USDA researcher Kay Behall and colleagues studied a small group of men and women as they followed a 10-week diet where all the grains were whole grains. The subjects, all of whom had slightly elevated cholesterol, showed significant reductions in both systolic and diastolic blood pressure when whole grains were added. They also lost about 1kg during the course of the study– although the whole grain diet was higher in calories than a control low-fat diet with refined grains used at the start of the study.
Journal of the American Dietetic Association, September 2006; vol 106(9):1445-9

Researchers at the University of Rhode Island, in a six-month study headed up by Kathleen Melanson, found that whole grain cereals helped 180 overweight adults lose weight while increasing their consumption of fiber, magnesium and vitamin B-6.
Journal of the American Dietetic Association, September 2006; vol 106(9):1380-8