Whole grains

Many public health campaigns focus on fruit and vegetable intake, but perhaps a wiser approach would be to expand the focus to whole grains, nuts, and seeds. Researchers analyzed Canadian eating habits against dietary recommendations, and then calculated the disease burden attributable to not meeting specific dietary guidelines. From there, they were able to calculate the direct (hospital visits, medicine, etc.) and indirect (labor) costs associated with not meeting specific dietary recommendations. They found that $13.8 billion (in CAD) per year can be attributed to an unhealthy diet, which is more than the economic burden of not getting enough exercise (at $9.3 billion). Additionally, they found that not getting enough whole grains and not getting enough nuts and seeds were the two biggest contributors to this cost, at $3.3 billion each.
PLoS One. 2018 Apr 27;13(4):e0196333. (Lieffers JRL et al.)

Visceral fat is a dangerous type of abdominal fat that can surround vital organs like the liver. To see if grain choices might play a role in this fat distribution, researchers randomly assigned 50 Japanese men with a BMI of 23 or greater (midway through the “healthy weight” range or heavier) to a diet with whole grain bread or white bread for 12 weeks, and had their visceral fat estimated using tomography scans. After the 12-week study, the whole grain group lost 4 cm of visceral fat around their middle, while the white bread group showed no significant changes.
Plant Foods and Human Nutrition. 2018 Apr 18. [Epub ahead of print.] (Kikuchi Y et al.)

Refined wheat and rice noodles are common staple foods throughout Asia today, so replacing some of these foods with whole grain versions could go a long way in improving health. To test the impact, researchers randomly assigned 84 healthy adults (some with mildly high cholesterol) in Taiwan to an oat noodle group or a refined wheat noodle group, providing them with 100 grams (about 1 ½ cups cooked) of their respective noodles across 1 or 2 meals each day for 10 weeks. After the 10-week study, the oat group reduced their total cholesterol by 17% and LDL-c (“bad”) cholesterol by 19% compared with the wheat noodle group. The oat noodle group also significantly lowered their blood pressure by 7-11%, but the wheat noodle group did not. The benefits tended to be stronger in people who started the study with slightly high cholesterol, but the results were still statistically significant for the group as a whole.
Journal of Food and Drug Analysis. 2018 April. [Epub ahead of print.] (Liao MY et al.)

It’s important to get your fiber from a variety of foods, since different sources of fiber are associated with different health benefits. Researchers analyzed the eating patterns of 2,135 patients with breast cancer and 2,571 controls to see how different foods and fibers might relate to breast cancer risk. Those eating the most fiber (more than 26.5 grams per day) were 25% less likely to have breast cancer than those eating less than 15.2 grams of fiber per day. Similarly, those eating the most beans (more than 3.9 oz per day) and grains (more than 13.8 oz per day, of both whole and refined grains) were 19% and 18% less likely to have breast cancer, respectively, than those eating the least amount of beans and grains.
Cancer Medicine. 2018 Mar 23. [Epub ahead of print] (Sangaramoorthy M et al.)

The link between whole grains and colorectal cancer prevention is well established, but researchers wonder how this relationship plays out in patients who have already been diagnosed with colon cancer. In this study, researchers analyzed the eating habits and health status of 1,024 patients with stage III colon cancer. After 7 years, patients eating 3 or more servings of refined grains per day had a significantly higher risk of cancer reoccurrence or death from any cause. Replacing 1 serving of refined grains with 1 serving of whole grains daily was linked with a 23% lower risk of cancer reoccurrence or death from any cause. Eating 3 or more servings of whole grains daily trended towards lower risk as well, but the relationship was not statistically significant.
JNCI Cancer Spectrum. 2018 Feb;2(2):pky017. (Brown JC et al.)

Lifestyle habits, like diet, are an important part of a cancer-protective strategy. To see if diet relates to prostate cancer risk, researchers analyzed the eating habits of 754 men with prostate cancer, and 1,277 controls without prostate cancer. Those most closely following a Mediterranean diet were 34% less likely to have an aggressive form of prostate cancer than those not following a Mediterranean diet. A Western diet (filled with fast food, sweets, and red meat) and a prudent diet (filled with low fat dairy, juice, produce, and whole grains) were not found to be linked to prostate cancer risk.
Journal of Urology. 2018 Feb;199(2):430-437. (Castello A et al.)

The infrastructure for wheat breeding & milling is largely set up to favor refined flour, rather than whole grain flour. In this article, researchers from Washington State University define new quality targets for wheat breeders that take into account fermentation, the bran and germ of the grain, protein strength, and flavor. They also note that different wheats are recommended for different products (pastry, breads, or noodles), and make recommendations for testing breeding lines on the farm to ensure that the new variety will work for farmers, millers, bakers, and consumers alike.
Agroecology and Sustainable Food Systems. 2018 January 29. (Jones SS et al.) [Epub]

Stroke survivors are twice as likely to develop dementia compared to the general population. To see how diet relates to brain health in stroke survivors, researchers analyzed the eating patterns and brain function of 106 stroke survivors for more than 4 years. Those most closely following a “MIND diet” had a slower rate of cognitive decline than those who don’t follow a MIND diet. The MIND diet is a hybrid Mediterranean-DASH diet that emphasizes foods associated with brain health, including whole grains, green leafy vegetables, berries, nuts, olive oil, and fish. The Mediterranean diet is well-known for its brain benefits, so it’s not surprising that this new diet inspired by the Mediterranean diet is also showing promise for brain health. 
Presentation at the American Heart Association Meeting. Los Angeles, California. January 25, 2018. 

Aortic stiffness, a thickening or hardening of the body’s main artery, naturally occurs due to aging but is accelerated by conditions like obesity and diabetes. Because aortic stiffness is a significant predictor of heart disease, heart failure and stroke, scientists wonder if lifestyle choices can help delay this progression. Researchers recruited 22 obese men to look at the stiffness of the aorta and ask questions about their dietary intake (e.g. fruits, vegetables, whole grains, meat, dairy, milk, etc.). Of all food choices, whole grains were the only factor significantly associated with less aortic stiffness.
Nutrition. 2018 Jan;45:32-36. (Campbell M et al.)

The microbiome is increasingly under study, and researchers are especially interested in what the bacteria are doing in the body. Given that whole grains are full of diverse types of fiber including resistant starch and non-starch polysaccharide, researchers hypothesize that this whole grain fiber feeds intestinal bacteria and in turn, the bacteria produce molecules that are beneficial for myriad reasons. Chemicals produced by gut bacteria including various fatty acids may contribute to health by reducing tumor growth of colon cells, strengthening the immune system, and regulating the hormones that affect appetite. The researchers also note that several human and animal studies support this exciting hypothesis.
Food Research International. 2018 Jan;103:84-102. (Gong L et al.)