Switch to Whole Wheat for Better Liver Health

The liver is important for metabolism, so researchers wonder how substituting whole grains might impact liver health. To assess this relationship, 50 overweight middle-aged adults were randomly assigned to a diet with 5 servings of whole wheat foods per day or 5 servings of refined wheat foods per day for 12 weeks, and compliance was confirmed by measuring biomarkers of whole wheat intake (alkylresorcinol). The refined wheat diet significantly increased liver fat, indicating that it may contribute to the development of nonalcoholic fatty liver disease. On the other hand, the whole wheat diet prevented an increase in liver fat, and better maintained liver health.
American Journal of Clinical Nutrition. 2018 Dec 1;108(6):1264-1274. doi: 10.1093/ajcn/nqy204. (Schutte S et al.)