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Replacing Potatoes with Whole Grains Can Lower Gestational Diabetes Risk

Healthy food choices can be an important way to help prevent gestational diabetes, a type of diabetes that occurs during pregnancy. To learn more about types of foods that might be helpful or harmful, Harvard researchers analyzed the diets and health outcomes of over 15,000 women. They found that replacing two servings per week of potatoes with whole grains lowered the risk of gestational diabetes by 12% (compared to 10% for replacing potatoes with legumes, and 9% for replacing potatoes with other vegetables).
British Medical Journal. 2016 Jan 12;h6898. (Bao W et al.)

Different Oat Products Elicit Different Glycemic Responses

The Glycemic Index is a measure of how much a food spikes your blood sugar (0-55 is low, 56-69 is medium and 70-100 is high). To see if different oat products have different effects on blood sugar, researchers from Quaker Oats tested the Glycemic Index of 72 oat products. They found that steel cut oatmeal, large flake oatmeal, muesli, and granola produced a significantly lower Glycemic Response (53-56, in the low/medium range) than quick cooking and instant oatmeal (71-75, in the medium/high range). The scientists concluded that “smaller particle size and increased starch gelatinisation appear to increase the glycemic response.”
British Journal of Nutrition. 2015 Oct 28;114(8):1256-62. (Tosh SM et al.)

Whole Grains Offer Benefits Beyond Fiber

Whole grains are well known for their fiber; however, fiber is not the only benefit of a diet rich in whole grains. This study uses nutritional metabolomics (a field of that looks at how different foods affect metabolism) to explore how the different compounds in whole grains may affect metabolism, and suggests scientific reasons behind the health benefits of whole grains, beyond just their fiber content. Specifically, this analysis suggests that whole grains may have positive effects on insulin sensitivity and protein metabolism, and may contain other beneficial compounds, such as glycine betaine.
Proceedings of the Nutrition Society. 2015 Aug;74(3):320-7. doi: 10.1017/S0029665114001542. Epub 2014 Oct 23. (Ross AB et al.)

Fiber from Whole Grains May Reduce Diabetes Risk

Studies have shown that fiber (especially from whole grains) may lower diabetes risk in Americans, but researchers wanted to know if the same was true in Europe. Analyzing the eating patterns of over 26,000 participants from 8 nations in Western Europe, the scientists found that total fiber was associated with a lower risk of diabetes, along with fiber from whole grains and vegetables (but not fruit). The researchers then combined these results with the results of 18 additional studies, following over 617,000 participants, and found that fiber from whole grains was the most protective. Indeed, for every additional 10g of total fiber or cereal fiber (the fiber in whole grains), the risk of type 2 diabetes was 9% or 25% lower, respectively. However, these results were not significant after adjusting for weight, meaning that whole grains and fiber likely play an important role in weight maintenance, another risk factor for type 2 diabetes.
Diabetologia. 2015 May 29. [Epub ahead of print] (InterAct Consortium).

Whole Grains and Cereal Fiber Linked with Longevity

A growing body of research suggests that whole grains may help you live longer. Boston scientists analyzed data from over 367,000 adults, and found that those with the highest intake of whole grains had a 17% lower risk of death from all causes compared to those who ate the least whole grains. Additionally, those eating the most whole grains had a lower risk of several disease-specific deaths, ranging from 11% for respiratory disease, up to 48% for diabetes. Similarly, a high intake of cereal fiber (the fiber from grain foods) was associated with a 19% lower risk of death from all causes, and a 25-34% lower risk of disease specific deaths. Whole grains offer a healthy diversity of protective nutrients, and this research suggests that cereal fiber is certainly among them.
BMC Medicine. 2015 Mar 4;13:59 (Huang T et al.)

Whole Grain Oats Can Improve Insulin Sensitivity and Cholesterol

The benefits of oats on blood sugar and cholesterol are well known, but new research suggests that the gut might also be involved. In a small study in Utah, 24 mice were fed a diet of either whole grain oat flour or refined (low bran) oat flour for eight weeks. The whole grain group had vastly different gut microbiota (the friendly bacteria in the gut) than the refined oat group, including twice as many beneficial Lactobacillacea. Those fed the whole grain oats also had significantly improved insulin sensitivity (a measure of how well a body is able to regulate its own blood sugar), 9.9% lower total cholesterol and 11% lower non-HDL (a combination of LDL and VLDL or “bad cholesterol”). The researchers speculate that the changes in gut microbiota could be a mechanism for improved insulin sensitivity and cholesterol, and conclude that these findings “further confirm the beneficial effect of whole grain oats.”
Journal of Nutrition. 2014 Dec 10. (Zhou A et al.)

Breakfast Cereal Associated with Higher Whole Grain Intake and Other Health Benefits

A study commissioned by the Australian Breakfast Cereal Manufacturers Forum analyzed 232 articles to investigate the health benefits and risks of eating cereal. The researchers found that while breakfast cereal consumption of any type is associated with diets higher in vitamins and minerals and lower in fat and a lower body mass index and less risk of being overweight or obese, whole grain breakfast cereal consumption provided even more benefits. Specifically, the study found that oat and barley based cereals can help lower cholesterol, and whole-grain or high-fiber breakfast cereals are associated with a lower risk of diabetes and higher intakes of protein, fiber, niacin, folate, calcium, and zinc. Additionally, the study found that those who eat breakfast cereal regularly have higher whole-grain consumption per day.
Advances in Nutrition. 2014 Sep 15;5(5):636S-73S, (Williams PG et al.)

Whole Grains Lower Insulin and Triglycerides in People with Metabolic Syndrome

Studies suggest a relationship between whole grain intake and insulin action. In a study in Italy, 53 adults (40-65 years old) with metabolic syndrome followed one of two different 12-week diets. One group consumed their standard diet, but replacing all grains with whole grains, and one group consumed their standard diet, but choosing only refined cereals. Researchers found that the whole grain group had significantly lower levels of post-meal insulin (29%) and triglyceride levels (43%) than before the 12-week test period, thus reducing the risk for heart disease and type 2 diabetes. Based on these findings, the researchers suggest that “the whole-grain diet was able to improve insulin action” after meals, thus providing clues about how whole grain diets reduce the risk of chronic disease.
Nutrition, Metabolism and Cardiovascular Diseases. 2014 August;24(8):837-844. (R. Giacco et al.)

MANY ANTIOXIDANTS IN WHOLE GRAINS

While fruits and vegetables are known as sources of healthy antioxidants and phenolic compounds, research increasingly shows that whole grains contain them too. In this review, researchers analyzed the total phenolic contents, phenolic acid profile and antioxidant activity of several whole grains, including wheat, corn, rice, barley, sorghum, rye, oat and millet. The review shows that whole grains contain a number of phytochemicals (including antioxidants) and significantly exhibit antioxidant activity. Researchers conclude that the consumption of whole grains is considered to have significant health benefits including prevention of chronic diseases such as cardiovascular disease, diabetes, and cancer because of the contribution of phenolic compounds. 
Critical Reviews in Food Science and Nutrition. 2014 July 30. [epub ahead of print] (Van Hung P et al.)

OATS REDUCE INFLAMMATORY MARKERS IN TYPE 2 DIABETES

Inflammation has been linked to many diseases, so understanding how to reduce inflammation is important. In a small study in Scotland, 22 people with type 2 diabetes participated in a randomized cross-over study, which consisted of two 8-week interventions with either an oat-enriched diet (their normal diet with oats replacing some of the carbohydrates; average intake of oats was 131g/day, or the equivalent of more than 1 ½ cups uncooked rolled oats) or a diet based on the standard dietary advice from Diabetes UK (average intake of oats was only 5g/day). Researchers then assessed the microparticle concentrations (a marker of inflammation) of patients after each diet and found that the oat-enriched diet significantly improved these risk factors for inflammation.  
Molecular Nutrition and Food Research. 2014 June;58(6):1322-32. (Zhang X et al.) 

Sorghum Reduces Glucose, Insulin Response

At the University of Arkansas, researchers conducted a small randomized crossover trial with 10 healthy men, to compare the impact on blood sugar of eating two different whole grain muffins: a whole sorghum muffin and a whole wheat muffin, each with 50g of total starch. Glucose response averaged 35% lower after the sorghum muffin, leading researchers to suggest that whole grain sorghum could be a good ingredient choice for managing glucose and insulin levels.
Food and Function. 2014 May;5(5):894-9. (Poquette et al.)

Brown Rice Reduces Diabetes Risk

At the Madras Diabetes Research Foundation in India, researchers carried out a randomized crossover trial in which they studied the effects of three diets on fifteen overweight Asian Indians. Test meals were identical for the three groups except for the type of rice (brown or white) and the addition of legumes. Fasting serum insulin was measured at the beginning and end of each 5-day test period, during which the subjects underwent continuous glucose monitoring. The scientists found that IAUC (incremental area under the curve, a measure of blood sugar management) was 19.8% lower with brown rice and 22.9% lower with brown rice and legumes, as compared to white rice. Fasting insulin was also markedly lower in the two brown rice phases of the study.
Diabetes Technology and Therapeutics. 2014 May; 16(5);317-25. (Mohan et al.)

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