Since wheat constitutes about two-thirds of the grains eaten in the United States, most U.S. studies of “whole grains” in the aggregate can be considered to attest to the benefits of whole wheat. So on this page, we’ve limited the universe to studies that focus in on the benefits of particular varieties or forms of whole wheat.

Antioxidants High, in Emmer and Einkorn

In Ankara, Turkey, scientists at Hacettepe University’s Department of Food Engineering compared 18 ancients wheats (12 emmer, 6 einkorn) with 2 modern bread wheats, to assess their total phenolics and flavonoids, phenolic acids, lutein, total yellow pigment, and total radical scavenging capacities. Results showed “remarkably higher total antioxidant activity” in emmer varieties, and “quite high levels of lutein” in the einkorn samples. In conclusion, the findings were considered to be key to “breeding wheat varieties for higher concentration and better composition of health-beneficial phytochemicals.”
Journal of Agricultural and Food Chemistry, August 27, 2008; 56(16): 7285-92

Organic Wheat Judged Tastier

Scientists at the University of Alberta baked whole wheat bread using the same cultivar of hard red spring wheat grown both conventionally and organically. They then asked 384 consumers to rate the taste – once, with unlabeled samples and no knowledge of the different origins, and again, after the breads had been labeled and the different growing conditions described. Consumers rated the taste of the organic bread higher both in the blind test and the informed test. Their ratings were unaffected by information on the environmental benefits of organic farming, but they liked the organic bread even more after learning of the potential health benefits of organically-grown foods.
Journal of Food Science, May 2008; 73(4): H50-7

“Whole” Whole Wheat Satisfies Longer

Researchers in Malmö, Sweden conducted a blind cross-over trial with 13 healthy adults to see If bread made largely with intact wheat kernels satisfied subjects longer than bread made with whole wheat flour, or refined wheat flour, and how the addition of vinegar would affect satiety. (Acetic acid, or vinegar, is known to increase satiety and lower postprandial blood glucose and insulin response.) The whole-kernel wheat bread with vinegar satisfied longest, even though it had the same amount of fiber as the whole wheat flour bread.
Nutrition Journal, April 27, 2008; 7:12

Ancient Wheats Higher in Healthy Carotenoids

Canadian researchers from the Food Research Program, Agriculture and Agri-Food Canada evaluated several primitive and modern wheat species, and found the highest levels of carotenoids including lutein, zeaxanthin and beta-carotene in Einkorn. Durum, Kamut® and Khorosan had intermediate levels, while common bread or pastry wheat had the lowest levels of carotenoids.  The carotenoids studied are thought to be important to eye health, among other functions.
Journal of Agricultural and Food Chemistry, February 2007; 55(3): 787-94

Magnesium May Explain Diabetes Benefits of Whole Wheat

It’s thought that foods with a lower glycemic index may improve insulin sensitivity. Yet whole wheat bread, with a glycemic index almost identical to bread made with refined wheat, has been found to promote insulin sensitivity when compared to the “white bread.” Researchers at Pantox Laboratories in San Diego, California, hypothesize that magnesium may be responsible, and urged “the strong desirability of choosing whole grain products in preference to refined grains.”
Medical Hypotheses, 2005; 64(3): 619-27

Less Allergenic Wheats Identified

Scientists in Shizuoka, Japan screened 324 varieties of wheat from around the world, in an effort to find varieties less likely to trigger allergies to gluten, gliadin, and alpha-amylase inhibitor. Einkorn, along with rare varieties from Mexico, Ecuador, China, and Italy, were found to be among the least allergenic.
Journal of Nutritional Science and Vitaminology (Tokyo), June 2005; 51(3): 204-6

Ancient Wheat Breads Digested Differently

Researchers at the Royal Veterinary and Agricultural University, in Frederiksberg, Denmark, compared three different loaves: einkorn bread made with honey-salt leavening; naturally-leavened einkorn bread made with crushed whole grains; and commercial yeast bread made with modern wheat. The naturally-leavened einkorn loaves significantly reduced the gastrointestinal response of GIP (glucose-dependent insulinotrophic polypeptide), a hormone important in controlling insulin secretion. 
European Journal of Clinical Nutrition, October 2003; 57(1):1254-61

Wheat Flour Particle Size Doesn’t Affect Glycemic Response

USDA’s Agricultural Research Service, in Beltsville, MD, asked twenty-six healthy adults to consume four different samples: glucose solution, traditional white (refined) bread, conventional whole wheat bread, or bread made with ultra-fine whole wheat. The researchers then determined the subjects’ glycemic response, and determined that both whole wheat flours (conventional and ultra-fine) had similar effects. They concluded that “the particle size of whole grain wheat flour did not substantially affect glycemic responses.”
Journal of the American College of Nutrition, December 1999; 18(6):591-7